1: Farhan H, Hsu VW. Cdc42 and Cellular Polarity: Emerging Roles at the Golgi.
Trends Cell Biol. 2016 Apr;26(4):241-8. doi: 10.1016/j.tcb.2015.11.003. Epub 2015
Dec 17. Review. PubMed PMID: 26704441; PubMed Central PMCID: PMC4809763.
2: Alvarez-Miranda EA, Sinnl M, Farhan H. Alteration of Golgi Structure by
Stress: A Link to Neurodegeneration? Front Neurosci. 2015 Nov 12;9:435. doi:
10.3389/fnins.2015.00435. eCollection 2015. PubMed PMID: 26617486; PubMed Central
PMCID: PMC4641911.
3: Cottarel J, Plissonnier ML, Kullolli M, Pitteri S, Clément S, Millarte V,
Si-Ahmed SN, Farhan H, Zoulim F, Parent R. FIG4 is a hepatitis C virus
particle-bound protein implicated in virion morphogenesis and infectivity with
cholesteryl ester modulation potential. J Gen Virol. 2016 Jan;97(1):69-81. doi:
10.1099/jgv.0.000331. Epub 2015 Oct 29. PubMed PMID: 26519381.
4: Stadel D, Millarte V, Tillmann KD, Huber J, Tamin-Yecheskel BC, Akutsu M,
Demishtein A, Ben-Zeev B, Anikster Y, Perez F, Dötsch V, Elazar Z, Rogov V,
Farhan H, Behrends C. TECPR2 Cooperates with LC3C to Regulate COPII-Dependent ER
Export. Mol Cell. 2015 Oct 1;60(1):89-104. doi: 10.1016/j.molcel.2015.09.010.
PubMed PMID: 26431026.
5: Baschieri F, Farhan H. Endomembrane control of cell polarity: Relevance to
cancer. Small GTPases. 2015;6(2):104-7. doi: 10.1080/21541248.2015.1018402.
Review. PubMed PMID: 26156751; PubMed Central PMCID: PMC4601278.
6: Millarte V, Boncompain G, Tillmann K, Perez F, Sztul E, Farhan H.
Phospholipase C γ1 regulates early secretory trafficking and cell migration via
interaction with p115. Mol Biol Cell. 2015 Jun 15;26(12):2263-78. doi:
10.1091/mbc.E15-03-0178. Epub 2015 Apr 22. PubMed PMID: 25904324; PubMed Central
PMCID: PMC4462944.
7: Baschieri F, Uetz-von Allmen E, Legler DF, Farhan H. Loss of GM130 in breast
cancer cells and its effects on cell migration, invasion and polarity. Cell
Cycle. 2015;14(8):1139-47. doi: 10.1080/15384101.2015.1007771. PubMed PMID:
25892554; PubMed Central PMCID: PMC4612654.
8: Farhan H. Systems biology of the secretory pathway: what have we learned so
far? Biol Cell. 2015 Jul;107(7):205-17. doi: 10.1111/boc.201400065. Epub 2015 May
6. Review. PubMed PMID: 25756903.
9: Genau HM, Huber J, Baschieri F, Akutsu M, Dötsch V, Farhan H, Rogov V,
Behrends C. CUL3-KBTBD6/KBTBD7 ubiquitin ligase cooperates with GABARAP proteins
to spatially restrict TIAM1-RAC1 signaling. Mol Cell. 2015 Mar 19;57(6):995-1010.
doi: 10.1016/j.molcel.2014.12.040. Epub 2015 Feb 12. PubMed PMID: 25684205.
10: Tillmann KD, Reiterer V, Baschieri F, Hoffmann J, Millarte V, Hauser MA,
Mazza A, Atias N, Legler DF, Sharan R, Weiss M, Farhan H. Regulation of Sec16
levels and dynamics links proliferation and secretion. J Cell Sci. 2015 Feb
15;128(4):670-82. doi: 10.1242/jcs.157115. Epub 2014 Dec 19. PubMed PMID:
25526736.
11: McEwan DG, Richter B, Claudi B, Wigge C, Wild P, Farhan H, McGourty K, Coxon
FP, Franz-Wachtel M, Perdu B, Akutsu M, Habermann A, Kirchof A, Helfrich MH,
Odgren PR, Van Hul W, Frangakis AS, Rajalingam K, Macek B, Holden DW, Bumann D,
Dikic I. PLEKHM1 regulates Salmonella-containing vacuole biogenesis and
infection. Cell Host Microbe. 2015 Jan 14;17(1):58-71. doi:
10.1016/j.chom.2014.11.011. Epub 2014 Dec 11. PubMed PMID: 25500191.
12: Spinnenhirn V, Farhan H, Basler M, Aichem A, Canaan A, Groettrup M. The
ubiquitin-like modifier FAT10 decorates autophagy-targeted Salmonella and
contributes to Salmonella resistance in mice. J Cell Sci. 2014 Nov 15;127(Pt
22):4883-93. doi: 10.1242/jcs.152371. Epub 2014 Sep 30. PubMed PMID: 25271057.
13: Baschieri F, Confalonieri S, Bertalot G, Di Fiore PP, Dietmaier W, Leist M,
Crespo P, Macara IG, Farhan H. Spatial control of Cdc42 signalling by a
GM130-RasGRF complex regulates polarity and tumorigenesis. Nat Commun. 2014 Sep
11;5:4839. doi: 10.1038/ncomms5839. PubMed PMID: 25208761; PubMed Central PMCID:
PMC4449154.
14: Reiterer V, Eyers PA, Farhan H. Day of the dead: pseudokinases and
pseudophosphatases in physiology and disease. Trends Cell Biol. 2014
Sep;24(9):489-505. doi: 10.1016/j.tcb.2014.03.008. Epub 2014 May 10. Review.
PubMed PMID: 24818526.
15: Krug AK, Gutbier S, Zhao L, Pöltl D, Kullmann C, Ivanova V, Förster S, Jagtap
S, Meiser J, Leparc G, Schildknecht S, Adam M, Hiller K, Farhan H, Brunner T,
Hartung T, Sachinidis A, Leist M. Transcriptional and metabolic adaptation of
human neurons to the mitochondrial toxicant MPP(+). Cell Death Dis. 2014 May
8;5:e1222. doi: 10.1038/cddis.2014.166. PubMed PMID: 24810058; PubMed Central
PMCID: PMC4047858.
16: Mazza A, Gat-Viks I, Farhan H, Sharan R. A minimum-labeling approach for
reconstructing protein networks across multiple conditions. Algorithms Mol Biol.
2014 Feb 9;9(1):1. doi: 10.1186/1748-7188-9-1. PubMed PMID: 24507724; PubMed
Central PMCID: PMC3933684.
17: Reitere V, Baschieri F, Millarte V, Farhan H. Methods to study signaling at
the Golgi apparatus. Methods Cell Biol. 2013;118:345-58. doi:
10.1016/B978-0-12-417164-0.00021-5. PubMed PMID: 24295317.
18: Reiterer V, Fey D, Kolch W, Kholodenko BN, Farhan H. Pseudophosphatase STYX
modulates cell-fate decisions and cell migration by spatiotemporal regulation of
ERK1/2. Proc Natl Acad Sci U S A. 2013 Jul 30;110(31):E2934-43. doi:
10.1073/pnas.1301985110. Epub 2013 Jul 11. PubMed PMID: 23847209; PubMed Central
PMCID: PMC3732994.
19: Tillmann KD, Millarte V, Farhan H. Regulation of traffic and organelle
architecture of the ER-Golgi interface by signal transduction. Histochem Cell
Biol. 2013 Sep;140(3):297-306. doi: 10.1007/s00418-013-1118-5. Epub 2013 Jul 3.
Review. PubMed PMID: 23821161.
20: Steeb B, Claudi B, Burton NA, Tienz P, Schmidt A, Farhan H, Mazé A, Bumann D.
Parallel exploitation of diverse host nutrients enhances Salmonella virulence.
PLoS Pathog. 2013;9(4):e1003301. doi: 10.1371/journal.ppat.1003301. Epub 2013 Apr
25. PubMed PMID: 23633950; PubMed Central PMCID: PMC3636032.
21: Baschieri F, Farhan H. Crosstalk of small GTPases at the Golgi apparatus.
Small GTPases. 2012 Apr-Jun;3(2):80-90. doi: 10.4161/sgtp.19842. Review. PubMed
PMID: 22790194; PubMed Central PMCID: PMC3408981.
22: Millarte V, Farhan H. The Golgi in cell migration: regulation by signal
transduction and its implications for cancer cell metastasis.
ScientificWorldJournal. 2012;2012:498278. doi: 10.1100/2012/498278. Epub 2012 May
1. Review. PubMed PMID: 22623902; PubMed Central PMCID: PMC3353474.
23: Zacharogianni M, Kondylis V, Tang Y, Farhan H, Xanthakis D, Fuchs F, Boutros
M, Rabouille C. ERK7 is a negative regulator of protein secretion in response to
amino-acid starvation by modulating Sec16 membrane association. EMBO J. 2011 Aug
16;30(18):3684-700. doi: 10.1038/emboj.2011.253. PubMed PMID: 21847093; PubMed
Central PMCID: PMC3173787.
24: Wild P, Farhan H, McEwan DG, Wagner S, Rogov VV, Brady NR, Richter B, Korac
J, Waidmann O, Choudhary C, Dötsch V, Bumann D, Dikic I. Phosphorylation of the
autophagy receptor optineurin restricts Salmonella growth. Science. 2011 Jul
8;333(6039):228-33. doi: 10.1126/science.1205405. Epub 2011 May 26. PubMed PMID:
21617041; PubMed Central PMCID: PMC3714538.
25: Farhan H, Rabouille C. Signalling to and from the secretory pathway. J Cell
Sci. 2011 Jan 15;124(Pt 2):171-80. doi: 10.1242/jcs.076455. PubMed PMID:
21187344.
26: Farhan H, Wendeler MW, Mitrovic S, Fava E, Silberberg Y, Sharan R, Zerial M,
Hauri HP. MAPK signaling to the early secretory pathway revealed by
kinase/phosphatase functional screening. J Cell Biol. 2010 Jun
14;189(6):997-1011. doi: 10.1083/jcb.200912082. PubMed PMID: 20548102; PubMed
Central PMCID: PMC2886346.
27: Farhan H, Hauri HP. Membrane biogenesis: networking at the ER with atlastin.
Curr Biol. 2009 Oct 13;19(19):R906-8. doi: 10.1016/j.cub.2009.08.029. Review.
PubMed PMID: 19825355.
28: Reiterer V, Maier S, Sitte HH, Kriz A, Rüegg MA, Hauri HP, Freissmuth M,
Farhan H. Sec24- and ARFGAP1-dependent trafficking of GABA transporter-1 is a
prerequisite for correct axonal targeting. J Neurosci. 2008 Nov
19;28(47):12453-64. doi: 10.1523/JNEUROSCI.3451-08.2008. PubMed PMID: 19020038;
PubMed Central PMCID: PMC4503341.
29: Farhan H, Weiss M, Tani K, Kaufman RJ, Hauri HP. Adaptation of endoplasmic
reticulum exit sites to acute and chronic increases in cargo load. EMBO J. 2008
Aug 6;27(15):2043-54. doi: 10.1038/emboj.2008.136. Epub 2008 Jul 24. PubMed PMID:
18650939; PubMed Central PMCID: PMC2516884.
30: Korkhov VM, Milan-Lobo L, Zuber B, Farhan H, Schmid JA, Freissmuth M, Sitte
HH. Peptide-based interactions with calnexin target misassembled membrane
proteins into endoplasmic reticulum-derived multilamellar bodies. J Mol Biol.
2008 Apr 25;378(2):337-52. doi: 10.1016/j.jmb.2008.02.056. Epub 2008 Mar 4.
PubMed PMID: 18367207; PubMed Central PMCID: PMC4493858.
31: Maier S, Reiterer V, Ruggiero AM, Rothstein JD, Thomas S, Dahm R, Sitte HH,
Farhan H. GTRAP3-18 serves as a negative regulator of Rab1 in protein transport
and neuronal differentiation. J Cell Mol Med. 2009 Jan;13(1):114-24. doi:
10.1111/j.1582-4934.2008.00303.x. Epub 2008 Mar 14. PubMed PMID: 18363836; PubMed
Central PMCID: PMC3823040.
32: Farhan H, Reiterer V, Kriz A, Hauri HP, Pavelka M, Sitte HH, Freissmuth M.
Signal-dependent export of GABA transporter 1 from the ER-Golgi intermediate
compartment is specified by a C-terminal motif. J Cell Sci. 2008 Mar 15;121(Pt
6):753-61. doi: 10.1242/jcs.017681. Epub 2008 Feb 19. PubMed PMID: 18285449;
PubMed Central PMCID: PMC4497808.
33: Ruggiero AM, Liu Y, Vidensky S, Maier S, Jung E, Farhan H, Robinson MB, Sitte
HH, Rothstein JD. The endoplasmic reticulum exit of glutamate transporter is
regulated by the inducible mammalian Yip6b/GTRAP3-18 protein. J Biol Chem. 2008
Mar 7;283(10):6175-83. doi: 10.1074/jbc.M701008200. Epub 2007 Dec 31. PubMed
PMID: 18167356; PubMed Central PMCID: PMC4502942.
34: Farhan H, Reiterer V, Korkhov VM, Schmid JA, Freissmuth M, Sitte HH.
Concentrative export from the endoplasmic reticulum of the gamma-aminobutyric
acid transporter 1 requires binding to SEC24D. J Biol Chem. 2007 Mar
9;282(10):7679-89. Epub 2007 Jan 8. PubMed PMID: 17210573.
35: Farhan H, Schuster C, Klinger M, Weisz E, Waxenecker G, Schuster M, Sexl V,
Mudde GC, Freissmuth M, Kircheis R. Inhibition of xenograft tumor growth and
down-regulation of ErbB receptors by an antibody directed against Lewis Y
antigen. J Pharmacol Exp Ther. 2006 Dec;319(3):1459-66. Epub 2006 Sep 8. PubMed
PMID: 16963623.
36: Farhan H, Freissmuth M, Sitte HH. Oligomerization of neurotransmitter
transporters: a ticket from the endoplasmic reticulum to the plasma membrane.
Handb Exp Pharmacol. 2006;(175):233-49. Review. PubMed PMID: 16722239.
37: Seidel S, Singer EA, Just H, Farhan H, Scholze P, Kudlacek O, Holy M, Koppatz
K, Krivanek P, Freissmuth M, Sitte HH. Amphetamines take two to tango: an
oligomer-based counter-transport model of neurotransmitter transport explores the
amphetamine action. Mol Pharmacol. 2005 Jan;67(1):140-51. PubMed PMID: 15615700.
38: Korkhov VM, Farhan H, Freissmuth M, Sitte HH. Oligomerization of the
{gamma}-aminobutyric acid transporter-1 is driven by an interplay of polar and
hydrophobic interactions in transmembrane helix II. J Biol Chem. 2004 Dec
31;279(53):55728-36. Epub 2004 Oct 20. PubMed PMID: 15496410.
39: Farhan H, Korkhov VM, Paulitschke V, Dorostkar MM, Scholze P, Kudlacek O,
Freissmuth M, Sitte HH. Two discontinuous segments in the carboxyl terminus are
required for membrane targeting of the rat gamma-aminobutyric acid transporter-1
(GAT1). J Biol Chem. 2004 Jul 2;279(27):28553-63. Epub 2004 Apr 8. PubMed PMID:
15073174.
40: Sitte HH, Farhan H, Javitch JA. Sodium-dependent neurotransmitter
transporters: oligomerization as a determinant of transporter function and
trafficking. Mol Interv. 2004 Feb;4(1):38-47. Review. PubMed PMID: 14993475.
41: Klinger M, Farhan H, Just H, Drobny H, Himmler G, Loibner H, Mudde GC,
Freissmuth M, Sexl V. Antibodies directed against Lewis-Y antigen inhibit
signaling of Lewis-Y modified ErbB receptors. Cancer Res. 2004 Feb
1;64(3):1087-93. PubMed PMID: 14871842.
42: Cross HS, Kállay E, Farhan H, Weiland T, Manhardt T. Regulation of extrarenal
vitamin D metabolism as a tool for colon and prostate cancer prevention. Recent
Results Cancer Res. 2003;164:413-25. PubMed PMID: 12899539.
43: Farhan H, Wähälä K, Cross HS. Genistein inhibits vitamin D hydroxylases CYP24
and CYP27B1 expression in prostate cells. J Steroid Biochem Mol Biol. 2003
Mar;84(4):423-9. PubMed PMID: 12732287.
44: Farhan H, Cross HS. Transcriptional inhibition of CYP24 by genistein. Ann N Y
Acad Sci. 2002 Nov;973:459-62. PubMed PMID: 12485911.
45: Kállay E, Adlercreutz H, Farhan H, Lechner D, Bajna E, Gerdenitsch W,
Campbell M, Cross HS. Phytoestrogens regulate vitamin D metabolism in the mouse
colon: relevance for colon tumor prevention and therapy. J Nutr. 2002 Nov;132(11
Suppl):3490S-3493S. PubMed PMID: 12421875.
46: Farhan H, Wähälä K, Adlercreutz H, Cross HS. Isoflavonoids inhibit catabolism
of vitamin D in prostate cancer cells. J Chromatogr B Analyt Technol Biomed Life
Sci. 2002 Sep 25;777(1-2):261-8. PubMed PMID: 12270218.